Mitochondrial Matrix Reloaded with RNA

The Matrix Reloaded: New Insights from Type IV Collagen Derived Endogenous Angiogenesis Inhibitors and their Mechanism of Action

Angiogenesis, the process of neovascularization from parent blood vessels, is a prerequisite for many physiological and pathological conditions that is regulated by a balance between the levels of endogenous angiogenic stimulators and matrix reloaded angiogenic regulators. Several non-collagenous carboxy terminal end domains in chains of type IV collagen matrix reloaded molecules selectively in...

GRSF1 Regulates RNA Processing in Mitochondrial RNA Granules

Various specialized domains have been described in the cytosol and the nucleus; however, little is known about compartmentalization within the mitochondrial matrix. GRSF1 (G-rich sequence factor 1) is an RNA binding protein that was previously reported to localize in the cytosol. We found that an isoform of GRSF1 accumulates in discrete foci in the mitochondrial matrix. These foci are composed ...

THE RULES OF THE GAME , THE BURDEN OF NARRATIVE : ENTER THE MATRIX Diane

Much of the commercial success that Enter The Matrix has enjoyed is the result of its relationship with the Matrix trilogy, rather than the quality of play it offers. The game was released at the same time as The Matrix Reloaded (May 2003) and immediately became the fastest-selling title in its publisher’s history. The game is part of the Matrix franchise, but whatever its allegiances, it is a ...

The mineralized extracellular "matrix" reloaded: a tissue engineering perspective.

Mitochondrial nucleic acid binding proteins associated with diseases.

Mammalian mitochondrial DNA (mtDNA) exists in structures called nucleoids, which correspond to the configuration of nuclear DNA. Mitochondrial transcription factor A (TFAM), first cloned as an mtDNA transcription factor, is critical for packaging and maintaining mtDNA. To investigate functional aspects of TFAM, we identified many RNA-binding proteins as candidate TFAM interactors, including ERA...